Tung O Chan Selected Research

Adenosine (Adenocard)

9/2008	Cardiac-restricted overexpression of the A(2A)-adenosine receptor in FVB mice transiently increases contractile performance and rescues the heart failure phenotype in mice overexpressing the A(1)-adenosine receptor.
5/2007	A1 adenosine receptor upregulation accompanies decreasing myocardial adenosine levels in mice with left ventricular dysfunction.
11/2006	Regulated overexpression of the A1-adenosine receptor in mice results in adverse but reversible changes in cardiac morphology and function.

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Tung O Chan Research Topics

Disease

11	Heart Failure 09/2015 - 04/2004
4	Pathologic Processes 09/2015 - 03/2009
4	Inflammation (Inflammations) 09/2015 - 02/2006
4	Cardiomyopathies (Cardiomyopathy) 06/2010 - 04/2004
3	Cardiomegaly (Heart Hypertrophy) 08/2011 - 03/2009
3	Left Ventricular Dysfunction 08/2011 - 05/2007
2	Hypertrophy 01/2013 - 02/2006
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2012 - 09/2008
2	Ischemia 01/2012 - 05/2007
2	Neoplasms (Cancer) 11/2011 - 01/2003
2	Necrosis 08/2010 - 03/2009
1	Heart Diseases (Heart Disease) 09/2015
1	Ischemic Stroke 04/2013
1	Body Weight (Weight, Body) 01/2012
1	Fibrosis (Cirrhosis) 01/2012
1	Diabetes Mellitus 11/2011
1	Bradycardia 06/2010
1	Sudden Death 06/2010
1	Heart Block 06/2010
1	Cardiotoxicity 06/2010
1	Infections 10/2008

Drug/Important Bio-Agent (IBA)

5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2010 - 04/2004
4	CytokinesIBA 09/2015 - 04/2004
4	Purinergic P1 Receptors (Adenosine Receptor)IBA 01/2012 - 05/2007
3	NF-kappa B (NF-kB)IBA 01/2011 - 02/2006
3	Adenosine (Adenocard)FDA LinkGeneric 09/2008 - 11/2006
2	Sodium-Calcium ExchangerIBA 01/2013 - 08/2010
2	Adenosine Triphosphatases (ATPase)IBA 03/2011 - 08/2010
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 09/2015
1	MicroRNAs (MicroRNA)IBA 09/2015
1	Transcription Factors (Transcription Factor)IBA 09/2015
1	Glutamate Receptors (Glutamate Receptor)IBA 04/2013
1	src-Family KinasesIBA 04/2013
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 01/2013
1	phospholemmanIBA 02/2012
1	salicylhydroxamic acid (SHAM)IBA 01/2012
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 11/2011
1	Threonine (L-Threonine)FDA Link 11/2011
1	Phosphotransferases (Kinase)IBA 11/2011
1	Arginine Vasopressin (Argipressin)IBA 08/2011
1	Tetracycline (Achromycin)FDA LinkGeneric 08/2011
1	Vasopressins (Vasopressin)IBA 08/2011
1	Doxycycline (Periostat)FDA LinkGeneric 08/2011
1	Dihydrotachysterol (AT 10)IBA 08/2011
1	CaveolinsIBA 03/2011
1	Caveolin 3IBA 03/2011
1	Proteins (Proteins, Gene)FDA Link 03/2011
1	pyruvate dehydrogenase kinase 4IBA 01/2011
1	Glucose (Dextrose)FDA LinkGeneric 08/2010
1	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2010
1	Green Fluorescent ProteinsIBA 10/2008
1	CalsequestrinIBA 05/2007
1	Type I Tumor Necrosis Factor ReceptorsIBA 04/2004
1	Type II Tumor Necrosis Factor ReceptorsIBA 04/2004
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 04/2004
1	ErbB Receptors (EGF Receptor)IBA 01/2003

Therapy/Procedure

2	Therapeutics 01/2012 - 03/2011
1	Drug Therapy (Chemotherapy) 01/2003